Knockout Design & Consequence Viewer
Explore exon deletion, indel and point-mutation consequences with Ensembl annotations and local calculations.
Local predictions · free Ensembl annotationsLoading this browser tool…
How to use it
Fetch a gene and choose its canonical or another translated transcript. Select exons or enter a CDS edit, then inspect sequence, domain and NMD predictions. Gene data from Ensembl.
Keep your work
SVG/PNG maps, consequence CSV/text, FASTA and full reference/design JSON. Local storage is specific to this domain and browser. Export a backup before clearing site data.
Methods and source notes
Calculations and limitations appear beside the tool. Official funding rules and dated references live in the shared configuration; verify the active opportunity. Cost estimates are clearly hypothetical and editable. Educational explanations and diagrams are original. No public study datasets are imported or redistributed.
Privacy and local-data controls · Credits and licenses · Interpretation limits